Julian, Percy Lavon

1899-1975 · Contribution: 1930s-1960s

Chemical synthesis of physostigmine and steroid hormones from soybeans

Science & Medicine — collage image
Science & Medicine

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Impact on the world

His large-scale synthesis of cortisone, progesterone, and testosterone from plant sterols laid the foundation for the modern steroid drug industry, dramatically lowering the cost of these medicines.

Life & background

A research chemist and pioneer in synthesizing medicinal drugs from plants, Julian was the first to synthesize the natural compound physostigmine, used to treat glaucoma. His soybean-derived steroid synthesis work helped make cortisone and birth control hormones affordable and widely available. He held over 130 chemical patents during his career.

Sources

  1. Science History Institute; American Chemical Society (National Historic Chemical Landmark); U.S. patent record